PerOssal®

PerOssal® is intended for the restoration of bone defects. After thorough surgical debridement and under systemic or local antibiosis, it may be also implanted in infected or contaminated areas.

PerOssal® is a synthetic, biodegradable and osteoconductive bone substitute material for restoration and filling of bone defects. Its unique microporous structure ensures uniform uptake of liquid substances (such as antibiotics) and their controlled sustained release.

PerOssal® has a porous structure that allows the safe uptake of aqueous solutions: 0.5 ml per 6 pellets and 4 ml per 50 pellets.
These characteristics make PerOssal® the ideal carrier material.

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Description

Features
  • Nanocrystalline / porous
    Suitable as carrier material for aqueous solutions (such as antibiotics)
  • Custom loadable
    Targeted highly effective antibiotic protection of the bone substitute material and the surrounding tissue according to the individual antibiogram with minimum systemic side effects
  • Prolonged action
    After drenching with antibiotics controlled long-term (10 days) protection of the boner replacement material against colonization with sensitive bacterial pathogens
  • Biodegradable
    • Fully absorbed independence of the defect size, the implantation site and the quality of the surrounding bone typically within 6 months
    • No second procedure required for explantation
The Biological Basis

Composition:

  • 51.5% nanocrystalline hydroxyapatite
  • 48.5% calcium sulfate
Dosage Form and Packaging Sizes

PerOssal® are cylindrical pellets measuring 6 mm x 6 mm, with one spherical and one fl at end. Packaging sizes of 1×6, 2×6 and 1×50 pellets are available. The pellets are primarily packed into vials, which are protected by a double peel-off packaging (inner and outer sterile packaging).

Indications
  • PerOssal® is indicated for filling or reconstruction of bone defects
  • In case of infected or contaminated bone, PerOssal® is indicated after prior surgical debridement and with simultaneous systemic and/or local administration of antibiotics.
  • PerOssal® can be used for augmentation of autogenous bone.
Possible Areas of Application
  • Traumatology
  • Orthopaedic surgery
  • Spinal surgery
  • Maxillofacial surgery